Uncover novel biology, identify new pathways, discover genotype-phenotype relationships and regulatory circuits. Generate libraries with a variety of edits including insertions, deletions, and swaps across E. coli and yeast genomes.
Engineer metabolic pathways for better outcomes and optimize strains for better phenotypes. Target both native and heterologous genome-integrated pathways for editing.
Understand the biology of higher eukaryotes—including humans and plants—through yeast as a model system. Create large-scale variation in human disease genes expressed in yeast to elucidate their impact on phenotypes. Edit plant genes expressed in yeast to define synthetic pathways and increase production of high-value compounds.
Inscripta’s application note developed in collaboration with Dr. Markus Herrgård from Novo Nordisk details the generation of a ALE-derivated mutations engineering into E. coli genome
Inscripta’s application note details the generation of precision-engineered E. coli populations and analysis of pooled growth selection in the presence of inhibitory compounds
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