Uncover novel biology, identify new pathways, discover genotype-phenotype relationships and regulatory circuits. Generate libraries with a variety of edits including insertions, deletions, and swaps across E. coli and yeast genomes.
Engineer metabolic pathways for better outcomes and optimize strains for better phenotypes. Target both native and heterologous genome-integrated pathways for editing.
Understand the biology of higher eukaryotes—including humans and plants—through yeast as a model system. Create large-scale variation in human disease genes expressed in yeast to elucidate their impact on phenotypes. Edit plant genes expressed in yeast to define synthetic pathways and increase production of high-value compounds.
Build libraries with diverse edit types including insertions, deletions and swaps in coding and non-coding regions across the Escherichia coli and Saccharomyces cerevisiae genomes. Explore a wide variety of phenotypes with edited libraries, either in pools of cells or in isolated cells.
Readily available consumables kits for use with strains related to E. coli K‑12 strain MG1655 and B strain BL21:
Readily available consumables kits for use with strains related to yeast S. cerevisiae strain S288c:
In addition to specific strains supported by Inscripta™, the Onyx platform may allow you to edit other strains of E. coli and S. cerevisiae. Please reach out with any questions.
Questions? Jump to the Resources Page.
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